Systems for the controlled release of pilocarpine

US5869086A · kind A · utility

Assignee

• LTS Lohmann Therapie-Systeme AG · DE

Inventors

• Lothar Deurer · Koblenz, DE
• Karlheinz Otto · Vallendar, DE
• Thomas Hille · Neuwied, DE

Key dates

• Filing date: Mar 26, 1996
• Grant date: Feb 9, 1999
• Expiry date: Mar 26, 2016

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P27/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A transdermal therapeutic system for the controlled active substance release to the skin having a backing layer and a pressure sensitive adhesive reservoir layer, wherein the reservoir layer comprises a polymeric material, a plasticizer, and pilocarpine base or one of the pharmaceutically acceptable salts thereof. Furthermore, the use of a capsule made of a semipermeable membrane for the controlled release of pilocarpine, the capsule comprising the pilocarpine in encapsulated form and having an aperture in the capsular material, for the treatment of glaucoma.