Patent · US Expired

Detection system for mutagens that identifies mutagenic changes

US5869258A · kind A · utility

1Cited by

7References

9Claims

0Family size

Assignee

The Regents of the University of California · US

Inventors

Pauline Gee · Berkeley, US
Dorothy M. Maron · Orinda, US
Bruce Ames · Berkeley, US

Key dates

Filing date	May 28, 1997
Grant date	Feb 9, 1999
Priority date	—
Expiry date	May 28, 2017

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12R2001/42
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Six sets of Salmonella typhimurium strains are provided, all strains having low spontaneous mutation rates, and each set being sensitive to and diagnostic of one of the six possible base substitutions in DNA. Also provided are methods for making and using these S. typhimurium strains to detect, and establish the type of specific base substitution mutation induced by, mutagenic agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.