Recombinant enzymatically active calpain expressed in a baculovirus system
US5869336A · kind A · utility
79Cited by
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9Claims
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Key dates
| Filing date | Jul 17, 1997 |
| Grant date | Feb 9, 1999 |
| Priority date | — |
| Expiry date | Jul 17, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2799/026
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is directed to mammalian enzymatically active calpain produced in insect cells by recombinant means. Recombinant vectors and baculoviruses containing cDNA encoding the 80 kDa subunit, 30 kDa subunit, and both subunits are described. Methods for producing recombinant enzymatically active mammalian calpain are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.