Gel-fiberglass and a method for its preparation
US5869409A · kind A · utility
Inventor
Key dates
| Filing date | Aug 26, 1993 |
| Grant date | Feb 9, 1999 |
| Priority date | — |
| Expiry date | Aug 26, 2013 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T442/2992
- WIPO fieldMaterials, metallurgy
- WIPO sectorChemistry
Abstract
A gel-fiber glass (GFG) is a newly-formed sol-gel glass polymerized from tetramethoxysilane on the surface of activated glass wool fibers or activated fibrous glass. GFG is a support for trapped chemical or biochemical reagents. A thin layer of reagents trapped in gel glass during its preparation is present on the surface of a lattice of glass fibers. Columns for affinity chromatography were prepared from the GFG membranes with entrapped antigens or antibodies and were used to isolate different proteins, including tumor-associated antigens; GFG membrane demonstrated high effectiveness and stability, and can isolate proteins in extremely high amounts. The membranes can be used in diagnostic practice, generation of specific antibodies and therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.