Cyclic CS-1 peptidomimetics, compositions and methods of using same
US5869448A · kind A · utility
7Cited by
3References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 25, 1995 |
| Grant date | Feb 9, 1999 |
| Priority date | — |
| Expiry date | Aug 25, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/27
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention contemplates a cyclic peptide that inhibits the binding between the VLA-4 receptor expressed on inflammatory leukocytes and the fibronectin CS-1 peptide expressed on endothelial cells that are involved in immunoinflammatory disease states. Pharmaceutical compositions containing a contemplated cyclic peptide and processes for treating immunoinflammatory conditions using a binding-inhibitory cyclic peptide are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.