Cytotoxic T-cell epitopes

US5869453A · kind A · utility

Assignee

• The Council of the Queensland Institute of Medical Research · AU

Inventors

• Denis James Moss · Brisbane, AU
• Scott Burrows · Bald Hills, AU
• Rajiv Khanna · Bowen Bridge, AU
• Beverley Mavis Kerr · Cleveland, AU
• Jacqueline Burrows · Bebington, GB
• Andreas Suhrbier · Brisbane, AU

Key dates

• Filing date: Jan 27, 1997
• Grant date: Feb 9, 1999
• Expiry date: Jan 27, 2017

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides cytotoxic Epstein-Barr virus T-cell epitopes. The epitopes are selected from the group consisting of QAKWRLQTL, RYSIFFDY, HLAAQGMAY, YPLHEQHGM, SVRDRLARL, AVLLHEESM, VSFIEFVGW, FRKAQIQGL, PYLFWLAAI, TVFYNIPPMPL, PGDQLPGFSDGRACPV, VEITPYKPTW, and variants thereof. In addition, the present invention provides compositions including these epitopes for use in inducing CTL's in a subject.