Azole compounds with antimycotic activity for human and veterinary use
US5869512A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Feb 25, 1997 |
| Grant date | Feb 9, 1999 |
| Priority date | — |
| Expiry date | Feb 25, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D249/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula ##STR1## wherein R.sub.1 is chloro, fluoro, bromo or trifluoromethyl; PA1 R.sub.2 is hydrogen, chloro, fluoro, bromo or trifluoromethyl; PA1 Z is CH or N; PA1 R.sub.3, R.sub.4 and R.sub.5, which are the same or different, are hydrogen or C.sub.1 -C.sub.4 alkyl, with the proviso that R.sub.4 is different from R.sub.5 when R.sub.3 is hydrogen; PA1 X is O, S, SO or S0.sub.2 ; PA1 R.sub.6 is a C.sub.1 -C.sub.5 polyfluoroalkyl group containing at least two fluorine atoms and optionally other halogen atoms selected from the group consisting of chloro and bromo; processes for their preparation and pharmaceutical compositions containing them are described. The compounds of formula II-A are endowed with a marked wide range antimycotic acitivity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.