Boronic compound complexing reagents and complexes
US5869623A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Oct 22, 1997 |
| Grant date | Feb 9, 1999 |
| Priority date | — |
| Expiry date | Oct 22, 2017 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/54353
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Boron compound complexing reagents, intermediate reagents of those reagents, and methods of synthesizing these reagents are disclosed. These reagents, including those shown as General Formula II may be used, after further reactions described herein, to complex with boronic compounds, such as phenylboronic acid or derivatives thereof. ##STR1## In one embodiment, group Z comprises a spacer selected from a saturated or unsaturated chain of up to about 6 carbon equivalents in length, an unbranched saturated or unsaturated chain from about 6 to 18 carbon equivalents in length with at least one intermediate amide or disulfide moieties, and a polyethylene glycol chain of from about 3 to 12 carbon equivalents in length; group R.sub.2 is one of an alkyl and a methylene group with an electronegative moiety; and BAS is a biologically active species.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.