Human Kallikrein
US5869637A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 22, 1996 |
| Grant date | Feb 9, 1999 |
| Priority date | — |
| Expiry date | Jul 22, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present provides a polynucleotide which identifies and encodes a novel human kallikrein (HKLP). The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding HKLP. The invention also provides for the use of substantially purified HKLP and its agonists, antagonists, or inhibitors in the commercial production of recombinant proteins and in pharmaceutical compositions for the treatment of diseases associated with the expression of HKLP. Additionally, the invention provides for the use of antisense molecules to HKLP in pharmaceutical compositions for treatment of diseases associated with the expression of HKLP. The invention also describes diagnostic assays which utilize diagnostic compositions comprising the polynucleotide, fragments or the complement thereof, which hybridize with the genomic sequence or the transcript of polynucleotides encoding HKLP or anti-HKLP antibodies which specifically bind to HKLP.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.