Process for the purification of a 3-cephem-4-carboxylic acid derivative
US5869648A · kind A · utility
5Cited by
9References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 6, 1995 |
| Grant date | Feb 9, 1999 |
| Priority date | — |
| Expiry date | Jun 6, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D501/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a new process for the depletion of 7-amino-3-(E)-1-propen-1-yl!-3-cephem-4-carboxylic acid in mixtures of 7-amino-3-(Z)-1-propen-1-yl!-3-cephem-4-carboxylic acid and 7-amino-3-(E)-1-propen-1-yl!-3-cephem-4 carboxylic acid, by means of the crystalline hydrochloride or a metal or amine salt of 7-amino-3-(Z/E)-1-propen-1-yl!-3-cephem-4-carboxylic acid or by adsorption chromatography.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.