Automatic sequencer/genotyper having extended spectral response
US5871628A · kind A · utility
44Cited by
14References
37Claims
0Family size
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Key dates
| Filing date | Aug 22, 1996 |
| Grant date | Feb 16, 1999 |
| Priority date | — |
| Expiry date | Aug 22, 2016 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J2219/00702
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An advanced imaging spectrograph system provides for slab-gel DNA sequencing and genotyping with high throughput sequencing. The system is based on the integration of improved electrophoresis structures with an imaging spectrophotometer that records the entire emission spectra along an imaging line across a sequencing gel (or capillary array). The system includes spectral shape matching to improve dye identification allowing the use of dyes having nearly any emission spectra and allowing greater than four dye multiplexing.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.