Liquid immunoglobulin formulations
US5871736A · kind A · utility
61Cited by
1References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 7, 1997 |
| Grant date | Feb 16, 1999 |
| Priority date | — |
| Expiry date | Mar 7, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Immunoglobulin preparations, particularly liquid preparations of immunogllin G for intravenous infusion, are stabilized against dimer formation by the addition of one or more amphiphilic stabilizers. Preferred amphiphilic stabilizers are nicotinic acid derivatives, particularly nicotinamide, and naturally-occurring .alpha.-amino acids having a lipophilic side chain, for example phenylalanine, proline, leucine and isoleucine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.