Methods of using poxvirus p35 as a chemokine inhibitor and compositions therefore
US5871740A · kind A · utility
22Cited by
2References
29Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Sep 26, 1996 |
| Grant date | Feb 16, 1999 |
| Priority date | — |
| Expiry date | Sep 26, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/826
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A protein designated p35 binds to a number of the chemotaxis-stimulating cytokines known as chemokines. p35 may be used to treat conditions that are mediated by chemokines, such as inflammation. p35 is a secreted protein that can be purified from the culture supernatant of cells infected with certain viruses, or produced using recombinant DNA techniques. Isolated DNA sequences encoding p35 are provided, along with expression vectors comprising the p35 DNA, and purified p35 protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.