Patent · US Expired

ECDN protein and DNA encoding the same

US5871916A · kind A · utility

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5Claims
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Key dates

Filing dateMay 2, 1996
Grant dateFeb 16, 1999
Priority date
Expiry dateMay 2, 2016

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A DNA encoding a novel steroid hormone receptor-like protein was obtained from a human fetal lung cDNA library, and its structure was determined. Further, the protein encoded by the gene was isolated, identified, and designated as an ECDN protein. Furthermore, a protein encoded by a DNA lacking a part of the above gene was isolated, identified, and designated as an ECDN paucimolecular protein. It was proven that the ECDN paucimolecular protein was expressed in various cancer cells. Therefore, it is expected that it becomes possible to diagnose and treat cancers by analyzing the expression of the ECDN protein and the ECDN paucimolecular protein in a subject tissue. Furthermore, attained to develop novel pharmaceuticals can be developed by finding natural and synthetic compounds capable of binding specifically to the ECDN protein and the ECDN paucimolecular protein.

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