Modulators of anchoring protein function
US5871945A · kind A · utility
33Cited by
10References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 17, 1995 |
| Grant date | Feb 16, 1999 |
| Priority date | — |
| Expiry date | Jul 17, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/16
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides compositions and methods useful for isolating calcineurin as well as inhibiting calcineurin activity. The compositions are peptides that contain regions that are homologous to calcineurin-binding regions of AKAP 79. Also provided are methods for determining if a cell contains a calcineurin-binding and PKA-binding anchoring protein that are useful for identifying additional proteins that bind both calcineurin and PKA. Another aspect of the present invention is methods for enhancing expression of interleukin 2 by T cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.