Patent · US Expired

Use of a baculovirus to express and exogenous gene in a mammalian cell

US5871986A · kind A · utility

145Cited by
5References
36Claims
0Family size

Assignee

Inventor

Key dates

Filing dateSep 23, 1994
Grant dateFeb 16, 1999
Priority date
Expiry dateSep 23, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2710/14143
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed is a method of expressing an exogenous gene in a mammalian cell, involving infecting the cell with a baculovirus whose genome carries an exogenous gene, and growing the cell under conditions such that the gene is expressed. Also disclosed is a method of treating a gene deficiency disorder in a mammal by providing to a cell a therapeutically effective amount of a baculovirus whose genome carries an exogenous gene and growing the cell under conditions such that the exogenous gene is expressed in the mammal.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.