Patent · US Expired

Microscale fluid handling system

US5872010A · kind A · utility

648Cited by
44References
37Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 3, 1996
Grant dateFeb 16, 1999
Priority date
Expiry dateJul 3, 2016

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/25375
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A microscale fluid handling system that permits the efficient transfer of nanoliter to picoliter quantities of a fluid sample from the spatially concentrated environment of a microfabricated chip to "off-chip" analytical or collection devices for further off-chip sample manipulation and analysis is disclosed. The fluid handling system is fabricated in the form of one or more channels, in any suitable format, provided in a microchip body or substrate of silica, polymer or other suitable non-conductive material, or of stainless steel, noble metal, silicon or other suitable conductive or semi-conductive material. The microchip fluid handling system includes one or more exit ports integral with the end of one or more of the channels for consecutive or simultaneous off-chip analysis or collection of the sample. The exit port or ports may be configured, for example, as an electrospray interface for transfer of a fluid sample to a mass spectrometer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.