Combinations and methods for reducing antimicrobial resistance
US5872104A · kind A · utility
47Cited by
4References
132Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 27, 1994 |
| Grant date | Feb 16, 1999 |
| Priority date | — |
| Expiry date | Dec 27, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/801
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are novel methods, combinations of agents and kits for use in killing, or inhibiting the growth of, microorganisms. Enhanced antimicrobial action is provided by using a methylation inhibitor, as exemplified by using an agent that inhibits methylation or maturation of bacterial RNA in combination with, e.g., a macrolide lincosamide streptogramin B (MLS) antibiotic. The methods and compositions described may be employed to reduce the resistance of susceptible microorganisms to antimicrobial agents and thus to treat animals or patients with infections.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.