NF2 isoforms
US5872214A · kind A · utility
0Cited by
2References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 4, 1996 |
| Grant date | Feb 16, 1999 |
| Priority date | — |
| Expiry date | Apr 4, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel human and mouse NF2 transcript isoforms and proteins encoded thereby, are disclosed. The isoforms are found in a variety of tissue and tumor types and represent differential processing of genomic DNA sequences, at the level of transcription, resulting in variant proteins. The isoforms provide useful tools for the analysis of the normal function of tumor suppressor factors, such as the merlin protein, and also provide useful markers for the detection of NF2 disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.