Patent · US Expired

Therapeutic compositions and methods for inhibition and treatment of tumor associated angiogenesis

US5874081A · kind A · utility

36Cited by
2References
13Claims
0Family size

Assignee

Inventor

Key dates

Filing dateMar 13, 1997
Grant dateFeb 23, 1999
Priority date
Expiry dateMar 13, 2017

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/73
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Antibodies, including monoclonal antibodies, specific for proliferating/angiogenic human endothelial cells such as human umbilical vein endothelial cells and human umbilical artery endothelial cells, and conjugates of these antibodies with a toxin material or label, are useful for inhibition of angiogenesis or for treatment of angiogenesis-dependent disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.