Vaccine for enhanced production of IgA antibodies
US5874085A · kind A · utility
23Cited by
4References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 8, 1995 |
| Grant date | Feb 23, 1999 |
| Priority date | — |
| Expiry date | Mar 8, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention describes compositions and methods for optimizing IgA class switching in B cells. The compositions comprise a multivalent antigen receptor crosslinker, CD40 ligand or lipopolysaccharide, and the cytokines TGF-.beta., IL-4, and either IL-5 or IL-2. Methods of using the compositions are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.