Methods of screening for non-hormone compounds which effect modulation of polypeptide translation
US5874231A · kind A · utility
15Cited by
4References
40Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Aug 22, 1994 |
| Grant date | Feb 23, 1999 |
| Priority date | — |
| Expiry date | Aug 22, 2014 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/4703
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Method for screening for a non-hormone agent potentially useful to treat a hormone disorder. The method involves contacting a potential agent with a system containing a cellular component and a translation factor. The component and factor interact with one another in an intact normal cell in a manner responsive to the hormone to cause a modulation of translation in the cell. The method involves determining whether the agent causes a modulation of translation by the component and the factor analogous to that which occurs in intact cells in response to the hormone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.