Compositions and methods for modulating cell proliferation using growth factor-polysaccharide binding fusion proteins
US5874308A · kind A · utility
18Cited by
4References
27Claims
0Family size
Assignee
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Key dates
| Filing date | Jan 16, 1996 |
| Grant date | Feb 23, 1999 |
| Priority date | — |
| Expiry date | Jan 16, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/70
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods and compositions are provided for in vitro expansion of growth factor dependent cells. Expansion is effected through the use of growth factor conjugates that include a growth factor such as a steel factor and a polysaccharidase substrate binding region. The conjugates are immobilized by binding of the substrate binding region to a substrate of the polysaccharidase in a growth chamber for the cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.