2,2'-bridged bis-2,4-diaminoquinazolines

US5874438A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Rudolf Schohe-Loop · Wuppertal, DE
• Peter-Rudolf Seidel · Cologne, DE
• William Bullock · Wuppertal, DE
• Walter Hubsch · Wuppertal, DE
• Achim Feurer · Wilhelmsfeld, DE
• Hans-Georg Lerchen · Leverkusen, DE
• Georg Terstappen · Düsseldorf, DE
• Joachim Schuhmacher · Wuppertal, DE
• Franz-Josef van der Staay · Dronten, NL
• Bernard Schmidt · Lindlar, DE
• Richard J. Fanelli · Madison, US
• Jane C. Chisholm · Clinton, US
• Richard T. McCarthy · Madison, US

Key dates

• Filing date: Oct 11, 1996
• Grant date: Feb 23, 1999
• Expiry date: Oct 11, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D403/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to 2,2'-bridged bis-2,4-diaminoquinazolines of the general formula (I): ##STR1## in which the indicated substituents are as defined in the description. The invention also provides processes for the preparation of the compounds of the formula (I), their use for the preparation of drugs, and drugs containing said compounds.