Isotonic fat emulsion containing omega-3-fatty acids and use thereof

US5874470A · kind A · utility

Assignee

• B. Braun Melsungen AG · DE

Inventors

• Joerg Nehne · Kassel, DE
• Michael Boll · Homberg (Efze), DE

Key dates

• Filing date: Sep 6, 1994
• Grant date: Feb 23, 1999
• Expiry date: Sep 6, 2014

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/23
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Isotonic fat emulsions are provided which incorporate .omega.-3-fatty acids, .omega.-6-fatty acids, and medium-chain triglycerides. The emulsions are useful for parenteral application in post-aggression metabolism, in cases of chronic inflammatory diseases, and in neonatology and pediatrics. Due to the combination of .omega.-3-fatty acids and/or their physiologically acceptable esters with medium-chain-triglycerides, the medium-chain triglycerides are preferred to be oxidized in the organism, and the .omega.-3 fatty acids are protected from rapid oxidation, so that they are available to a higher extent for the formation of triply unsaturated eicosanoids. Furthermore, a liver protective effect is attained by the combination.