Cyclic depsipeptide sulfonylation, sulfenylation and phosphorylation process

US5874530A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Jurgen Scherkenbeck · Leverkusen, DE
• Andrew Plant · Leverkusen, DE
• Peter Jeschke · Eltville am Rhein, DE
• Achim Harder · Leverkusen, DE
• Norbert Mencke · Leverkusen, DE

Key dates

• Filing date: Apr 10, 1997
• Grant date: Feb 23, 1999
• Expiry date: Apr 10, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/6527
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to a process for the aromatic sulfonylation, sulfenylation, thiocyanation and phosphorylation of cyclic depsipeptides having 6 to 24 ring atoms which are synthesized from .alpha.-hydroxycarboxylic acids and .alpha.-amino acids and contain at least one phenyl radical, characterized in that these cyclic depsipeptides are reacted with sulfonylating, sulfenylating, thiocyanating or phosphorylating agents, optionally in the presence of catalysts, auxiliaries and/or diluents, to novel thus-obtained compounds, and to their use as endoparasiticides.