Production process and intermediate of tetrazole compound
US5874593A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 8, 1996 |
| Grant date | Feb 23, 1999 |
| Priority date | — |
| Expiry date | Feb 8, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There are disclosed an industrially favorable process for producing a tetrazole compound of general formula (1): ##STR1## characterized in that a nitrile of general formula (2): EQU R.sup.1 CN (2) is reacted with hydrazine or a salt thereof in the presence of a catalyst, followed by reaction with a nitrous acid compound of general formula (3): EQU ANO.sub.2 (3) or a nitrile of general formula (2) is reacted with hydrogen sulfide, followed by reaction with an alkyl halide of general formula (4): EQU R.sup.4 J (4) with hydrazine or a salt thereof, and then with a nitrous acid compound of general formula (3); and an intermediate of general formula (5): EQU R.sup.1 C(=R.sup.5)R.sup.6 (5) which is useful for the production of the tetrazole compound (in which R.sup.1 to R.sup.6, A and J in the above formulas are as defined in the specification).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.