Process of protecting a 1,2-aminoalcohol for reductive amination coupling
US5874601A · kind A · utility
0Cited by
3References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 5, 1996 |
| Grant date | Feb 23, 1999 |
| Priority date | — |
| Expiry date | Apr 5, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/1804
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process of protecting a 1,2- or 1,3-aminoalcohol for reductive amination coupling is provided. The alcohol is protected with trimethylsilyl chloride. Trimethylsilyl protected norepinephrine derivatives useful in the preparation of arbutamine are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.