Modified implant with bioactive conjugates on its surface for improved integration
US5876454A · kind A · utility
27Cited by
23References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 28, 1996 |
| Grant date | Mar 2, 1999 |
| Priority date | — |
| Expiry date | Jun 28, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/915
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention relates to a bioactive conjugate adapted to coat a metal implant outer surface, which has the following structural formula I: EQU --R--X--P I wherein, PA1 R is O or S, adapted to be covalently attached to an implant surface; PA1 X is selected from a bond, linear or branched chains of 1 to 30 covalently attached atoms of at least C, N, O Si or S, rings of 1 to 20 covalently attached atoms of at least C, N, O Si or S, and a combination thereof; and PA1 P is a bioactive molecule moiety which promotes tissue growth, stabilization and integration, and wherein said moiety retains its biological activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.