Patent · US Expired

Chemo-mechanical expansion delivery system

US5876741A · kind A · utility

42Cited by
4References
21Claims
0Family size

Assignee

Inventor

Key dates

Filing dateJul 15, 1997
Grant dateMar 2, 1999
Priority date
Expiry dateJul 15, 2017

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2533/70
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

System for delivery of a biologically active substance into an environment. The container is comprised of a single member or two mated members and defines first and second compartments. The container includes pores in at least a portion of the container defining the first compartment. The first compartment contains a polymer gel network which undergoes a volume expansion in response to an environmental condition which varies in the biological environment. The second compartment contains an effective amount of a biologically active compound and may include at least one passageway communicating with the biological environment. Drug delivery is initiated and continues only when the appropriate environmental condition or trigger is met, whereupon volume expansion of the polymer gel network causes the biologically active compound to be discharged into the biological environment.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.