Patent · US Expired

Antibodies specific for fragile X related proteins and method of using the same

US5876949A · kind A · utility

13Cited by
6References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 31, 1995
Grant dateMar 2, 1999
Priority date
Expiry dateMay 31, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q2600/158
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention relates to substantially pure FXR1 and FXR2 proteins and isolated nucleic acid molecules encoding the same. Recombinant expression vectors comprising nucleic acid sequences that encode FXR1 and FXR2 protein are also provided. Antibodies which bind to an epitope of FXR1 or FXR2, or FMR1 protein are also provided. The present invention also relates to methods of screening individuals for FMR1 deficiency using antibodies or nucleic acid molecules of the invention and pharmaceutical kits for accomplishing the same.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.