Patent · US Expired

Cytotoxic factor as is associated with multiple sclerosis, its detection and its quantification

US5876954A · kind A · utility

8Cited by
12References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 15, 1995
Grant dateMar 2, 1999
Priority date
Expiry dateFeb 15, 2015

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S436/828
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Gliotoxic factor in the isolated or purified state, characterized in that it possesses toxic activity with respect to human or animal astrocytic cells, having the effect of a cytomorphological disorganization of their network of intermediate filaments and/or a degradation of the proteins of said intermediate filaments and/or cell death, in particular by apoptosis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.