Fusion polypeptides comprising human serum albumin, nucleic acids encoding same, and recombinant expression thereof

US5876969A · kind A · utility

Inventors

• Reinhard Fleer · Les Ulis, FR
• Alain Fournier · ᐙᔂᓂᐲ Waswanipi, CA
• Jean-Dominique Guitton · Paris, FR
• Gerard Jung · Montlhéry, FR
• Patrice Yeh · Paris, FR

Key dates

• Filing date: Jan 31, 1997
• Grant date: Mar 2, 1999
• Expiry date: Jan 31, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/33
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Biologically active polypeptides comprising a therapeutically active polypeptide fused to human serum albumin or a natural variant thereof, methods for the preparation thereof, nucleotide sequences encoding such fusion polypeptides, expression cassettes comprising such nucleotide sequences, self-replicating plasmids containing such expression cassettes, and pharmaceutical compositions containing said fusion polypeptides.