Patent · US Expired

Thrombin inhibitor from the saliva of protostomia

US5876971A · kind A · utility

3Cited by

0References

29Claims

0Family size

Assignee

SCHERING CORPORATION · US

Inventors

Christiane Noeske-Jungblut · Berlin, DE
Wolf-Dieter Schleuning · San Pedro de la Cueva, MX
Alejandro Alagon · Cuernavaca, MX
Lourival Possani · Cuernavaca, MX
Delia Cuevas-Aguierre · Cuernavaca, MX
Peter Donner · Berlin, DE
Bernard Haendler · Berlin, DE
Ulrike Hechler · Berlin, DE

Key dates

Filing date	Aug 24, 1995
Grant date	Mar 2, 1999
Priority date	—
Expiry date	Aug 24, 2015

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to a natural protein or a protein that can be synthetically produced, which is a thrombin inhibitor and can be isolated from the saliva of insects which suck the blood of mammals. Preferred is the Triatoma pallidipennis insect. The protein is used for the treatment of thromboses or unstable angina or arteriosclerosis, or for the prevention of a reblockage of vessels after PTCA/PTA or for the prevention of blood clotting in hemodialysis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.