Method for introducing and expressing genes in animal cells and live invasive bacterial vectors for use in the same
US5877159A · kind A · utility
118Cited by
1References
24Claims
0Family size
Assignee
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Key dates
| Filing date | May 3, 1995 |
| Grant date | Mar 2, 1999 |
| Priority date | — |
| Expiry date | May 3, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/51
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for introducing and expressing genes in animal cells is disclosed comprising infecting said animal cells with live invasive bacteria, wherein said bacteria contain a eukaryotic expression cassette encoding said gene. The gene may encode, e.g., a vaccine antigen, an therapeutic agent, an immunoregulatory agent or a anti-sense RNA or a catalytic RNA.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.