Acellular pertussis vaccines and methods of preparing thereof
US5877298A · kind A · utility
9Cited by
5References
12Claims
0Family size
Inventors
Key dates
| Filing date | May 4, 1995 |
| Grant date | Mar 2, 1999 |
| Priority date | — |
| Expiry date | May 4, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A fimbrial agglutinogen preparation is prepared from a bordetella strain, particularly a B. pertussis strain, by a multiple step procedure involving extraction of the fimbrial agglutinogens from cell paste and concentrating and purifying the extracted material. The fimbrial agglutinogen preparation may be used to prepare acellular pertussis vaccines with other pertussis antigens, including pertussis toxin or toxoid thereof, the 69 kDa protein and filamentous hemagglutinin and other Bordetella antigens.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.