Tethered prodrugs
US5880097A · kind A · utility
13Cited by
2References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 4, 1996 |
| Grant date | Mar 9, 1999 |
| Priority date | — |
| Expiry date | Jan 4, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds wherein a biologically active molecule is coupled to a glutathione analog through a conjugated system which permits activation of the biologically active molecule while retaining the biologically active molecule tethered to the glutathione analog are useful as tethered prodrugs that slow the rate of clearance of an active biomolecule through the multidrug resistance pump.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.