Substituted oxazine and thiazine oxazolidinone antimicrobials
US5880118A · kind A · utility
18Cited by
3References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 2, 1997 |
| Grant date | Mar 9, 1999 |
| Priority date | — |
| Expiry date | Jul 2, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound of the Formula I: ##STR1## or pharmaceutically acceptable salts thereof wherein X, R, R.sup.1, R.sup.2, R.sup.3 and n are as defined in the disclosure. The oxazine and thiazine oxazolidinone derivatives are useful antimicrobial agents effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiply-resistant staphylococci, streptococci, and enterococci as well as anaerobic organisms such as Bacteroides spp. and Clostridia spp. species, and acid-fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.