Combination of fenofibrate and vitamin E, and method of use of same in therapeutic treatments
US5880148A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 2, 1996 |
| Grant date | Mar 9, 1999 |
| Priority date | — |
| Expiry date | Feb 2, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a novel combination of fenofibrate and a vitamin E substance which comprises: PA1 (a) a micronized mixture of fenofibrate with a solid surfactant, and PA1 (b) a vitamin E substance selected from the group consisting of tocopherols, their esters with organic acids, and mixtures thereof, wherein: PA1 (1) the micronized mixture contains 33 to 200 mg of fenofibrate and the amount of said vitamin E substance represents 100 to 600 IU, and PA1 (2) the ratio (Ra) of the amount of fenofibrate, expressed in mg, to the amount of vitamin E substance, expressed in IU, is between 0.33 and 2 mg/IU. It further relates to the method of use of this combination in therapeutic treatments.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.