Aryl, alkyl, alkenyl and alkynylmacrolides having immunosuppressive activity
US5880280A · kind A · utility
2Cited by
11References
1Claims
0Family size
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Key dates
| Filing date | Jun 15, 1994 |
| Grant date | Mar 9, 1999 |
| Priority date | — |
| Expiry date | Jun 15, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Aryl, alkyl, alkenyl and alkynyl macrolides of the general structural Formula I: ##STR1## have been prepared from suitable precursors by modification at C-30, C-33, and/or C-34 of the cyclohexyl ring. These macrolide immunosuppressants are useful in a mammalian host for the treatment of autoimmune diseases, infectious diseases and/or the prevention of rejection of foreign organ transplants and/or related afflictions, diseases and illnesses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.