Patent · US Expired

Seamless capsule and method of manufacturing the same

US5882680A · kind A · utility

150Cited by
4References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 3, 1996
Grant dateMar 16, 1999
Priority date
Expiry dateDec 3, 2016

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K9/14
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

There are provided a seamless capsule containing therein a large quantity of an active ingredient which is difficultly soluble in water and oil and a method of manufacturing the seamless capsule. Encapsulating liquid 1, in which the active ingredient is difficultly soluble in water and oil is suspended in oil as particles each having the mean particle diameter of less than 20 .mu.m, is enclosed in hydrophilic outer shells. This seamless capsule SC is manufactured in such a manner that from a multiple nozzle 7, suspension, in which the active ingredient which is difficultly soluble in water and oil is dispersed in oil and the active ingredient in thus obtained dispersion is pulverized to obtain particles each having the mean particle diameter of less than 20 .mu.m, as encapsulating liquid 1, and aqueous liquid of a shell forming substance, as outer shell forming liquid 3, are dropped into hardening liquid 10.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.