Inhibitors of factor Xa
US5883077A · kind A · utility
7Cited by
7References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 15, 1993 |
| Grant date | Mar 16, 1999 |
| Priority date | — |
| Expiry date | Dec 15, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The novel compounds include peptide aldehyde analogues having substantial potency and specificity as inhibitors of mammalian factor Xa are further disclosed. The compounds are thought useful as inhibitors of factor xa in vitro or as a therapeutic agent for the prevention and treatment of conditions characterized by abnormal thrombosis in mammals. Intermediates useful for the preparation of the novel compounds are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.