Method for inhibiting H. pylori infection in mammalian tissue
US5883079A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 12, 1998 |
| Grant date | Mar 16, 1999 |
| Priority date | — |
| Expiry date | May 12, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P1/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for treating and/or inhibiting gastric and duodenal ulcers, comprising administering a pharmaceutical composition comprising an oligosaccharide of Formula I EQU (NeuAc-.alpha.(2-3)-pGal-.beta.(1)-(--X--).sub.m --(--Y--).sub.n -).sub.p -Z wherein X=a chemical bond or a group capable of linking the p galactose to either the linking group Y or the multivalent support Z; wherein the C.sub.1 glycosidic oxygen of galactose may be replaced by N, S or C; Y=a linking group; Z=a multivalent support; m=0 or 1; n=0 or 1; and p=an integer of 2-1,000 is described. Also described is a method for treating and/or inhibiting gastric and duodenal ulcers, comprising administering a pharmaceutical composition comprising an oligosaccharide of Formula II EQU NeuAc-.alpha.(2-3)-pGal-.beta.(1)-A wherein A=a group capable of bonding to the p galactose; wherein the C.sub.1 glycosidic oxygen of galactose may be replaced by N, S or C.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.