Multiply substituted DTPA derivatives and their metal complexes, and their metal complexes, pharmaceutical agents that contain these complexes, their use in diagnosis and therapy, as well as process for the production of pharmaceutical agents

US5885548A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Franz-Karl Maier · Berlin, DE
• Michael Bauer · Berlin, DE
• Werner Krause · Plantsville, US
• Ulrich Speck · Berlin, DE
• Gabriele Schuhmann-Giampiere · Berlin, DE
• Andreas Muhler · Oderberg, DE
• Thomas Balzer · Berlin, DE
• Wolf-Rudiger Press · Berlin, DE

Key dates

• Filing date: Nov 30, 1995
• Grant date: Mar 23, 1999
• Expiry date: Nov 30, 2015

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/24
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to new, multiply substituted diethylenetriaminepentaacetic acid derivatives, their complexes and complex salts, that contain an element of atomic numbers 20-32, 39-51 or 57-83, pharmaceutical agents that contain these compounds, their use as contrast media and antidotes, and process for the production of pharmaceutical agents.