Process for preparing optically active amines
US5885787A · kind A · utility
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5Claims
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Key dates
| Filing date | Aug 25, 1997 |
| Grant date | Mar 23, 1999 |
| Priority date | — |
| Expiry date | Aug 25, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P41/007
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
In accordance with a novel process, (R)-amines of the formula ##STR1## in which R.sup.1, R.sup.2 and n have the meanings given in the description, can be prepared by reacting reating N-acyl-amines of the formula ##STR2## in which R.sup.1, R.sup.2, R.sup.3 and n have the meanings given in the description, PA2 with lipases which are suitable for cleaving the (R)-enantiomers of N-acyl-amines of the formula (II), in the presence of water and optionally in the presence of an organic diluent, at a pH of between 3.0 and 10.0 and at temperatures of between 0.degree. C. and 80.degree. C.
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