Patent · US Expired

Hepatic-directed compounds and reagents for preparation thereof

US5886143A · kind A · utility

31Cited by
10References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 7, 1994
Grant dateMar 23, 1999
Priority date
Expiry dateDec 7, 2014

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K2121/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Hepatic-directed compounds, reagents useful in making such compounds and associated methods and compositions are discussed. Hepatic-directed compounds are processed by metabolic mechanisms, which generally differ in degree or in kind from the metabolic mechanisms encountered by compounds which are not so directed. Reagents useful in the preparation of hepatic-directed compounds include a hexose cluster characterized by multiple hexose residues connected in an iteratively branched configuration. In one embodiment, the hexose cluster comprises at least four hexose residues with each branch of the configuration having two prongs. In another embodiment, the hexose cluster comprises at least nine hexose residues with each branch of the configuration having three prongs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.