Encapsulated high-concentration lipid a compositions as immunogenic agents to produce human antibodies to prevent or treat gram-negative bacterial infections
US5888519A · kind A · utility
19Cited by
5References
29Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 19, 1995 |
| Grant date | Mar 30, 1999 |
| Priority date | — |
| Expiry date | May 19, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention is directed to the production of antibodies against lipid A by using encapsulating slow-releasing delivery materials or devices containing concentrations of lipid A that are greater than could be given safely to humans in the absence of said materials or devices. The antibodies to lipid A can be used for binding the antibodies to the lipid A that are present in the lipopolysaccharide that coats the surface of the Gram-negative bacteria.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.