Stable cell lines expressing the CFTR protein or a mutant of this protein, tool for selecting molecules having an effect on the intracellular transport of these proteins
US5888722A · kind A · utility
9Cited by
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20Claims
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Key dates
| Filing date | Jun 12, 1997 |
| Grant date | Mar 30, 1999 |
| Priority date | — |
| Expiry date | Jun 12, 2017 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/382
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to a recombinant nucleic acid, characterized in that it comprises: PA1 a nucleotide sequence encoding (coding sequence) the normal CFTR protein, PA1 an epitope sequence located at the 3' end of the abovementioned coding sequence, PA1 a strong promoter sequence capable of controlling the expression of the abovementioned coding sequence and epitope sequence, when they are integrated into a determined cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.