Anti-human plasmin-.alpha..sub.2 -plasmin inhibitor complex antibodies, hybridomas, and immunological determination method
US5888749A · kind A · utility
1Cited by
7References
29Claims
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Key dates
| Filing date | Sep 21, 1992 |
| Grant date | Mar 30, 1999 |
| Priority date | — |
| Expiry date | Sep 21, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K16/40
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A first monoclonal antibody which specifically reacts with a human .alpha..sub.2 -plasmin inhibitor complex (PIC) and a human plasminogen; a second monoclonal antibody which reacts with PIC and also with a human .alpha..sub.2 -plasmin inhibitor; a third monoclonal antibody which reacts with PIC, but does not react with a human plasminogen and a human .alpha..sub.2 -plasmin inhibitor; hybridomas which secrete the first to third monoclonal antibodies, and an immunoassay using the first to third monoclonal antibodies.
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