Monoclonal antibodies against the plasmin-antiplasmin complex, a method for the preparation thereof and the use thereof

US5888753A · kind A · utility

Assignee

• Behring Diagnostics GmbH · DE

Inventors

• Johann Hock · Marburg, DE
• Hermann Pelzer · Cölbe, DE

Key dates

• Filing date: May 14, 1992
• Grant date: Mar 30, 1999
• Expiry date: May 14, 2012

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K16/40
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention relates to monoclonal antibodies (MAbs) and fragments thereof which have a specific affinity for the plasmin-antiplasmin complex and which display no affinity or only a very low affinity for the individual components of these complexes, and to antigens which can be defined and/or isolated with the aid of these antibodies or antibody fragments. The antibodies, antibody fragments and antigens can be used as diagnostic aid, active substance or active substance carrier.